Patent · US Expired

CCR-2 antagonist salt

US7473696B2 · kind B2 · utility

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Key dates

Filing dateOct 25, 2004
Grant dateJan 6, 2009
Priority date
Expiry dateFeb 5, 2025

Classification

  • Technology area (CPC A)Human Necessities
  • CPC primaryA61P43/00
  • WIPO fieldPharmaceuticals
  • WIPO sectorChemistry

Abstract

An efficient synthesis for the preparation of ((1R,3S)-3-isopropyl-3-{[3-(trifluoromethyl)-7,8-dihydro-1,6-naphthyridin-6(5H)-yl]carbonyl} cyclopentyl)[(3S,4S)-3-methoxytetrahydro-2H-pyran-4-yl]amine and its succinate salt are provided. The succinate salt is crystalline and has superior properties.

Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.