Apparatus and method for in-vivo plasmapheresis using periodic backflush containing anticoagulant
US7476210B2 · kind B2 · utility
6Cited by
30References
30Claims
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Key dates
| Filing date | Dec 29, 2005 |
| Grant date | Jan 13, 2009 |
| Priority date | — |
| Expiry date | Jan 6, 2027 |
Classification
- Technology area (CPC A)Human Necessities
- CPC primaryA61M2025/0037
- WIPO fieldMedical technology
- WIPO sectorInstruments
Abstract
Method for in-vivo plasmapheresis utilizing a plurality of elongated hollow microporous filter fibers periodically interrupt diffusion of blood plasma from a patient, and, for a selected time, directing backflush fluid into the fibers at a pressure and interval sufficient to cleanse the fiber pores, after which plasma diffusion is resumed. The backflush fluid, preferably a normal saline solution, may contain an anticoagulant such as heparin, citrate or NO donor in suitable concentration for systemic anti-coagulation or for treating the fiber for thromboresistance.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.