Quinolinone derivatives and uses thereof

US7476675B2 · kind B2 · utility

Assignee

• Roche Palo Alto LLC · US

Inventors

• David Bruce Repke · Palo Alto, US
• Russell Stephen Stabler · Mountain View, US
• Ralph New Harris, III · Redwood City, US

Key dates

• Filing date: Jul 27, 2005
• Grant date: Jan 13, 2009
• Expiry date: Mar 16, 2027

Classification

• Technology area (CPC C): Chemistry; Metallurgy
• CPC primary: C07D405/06
• WIPO field: Pharmaceuticals
• WIPO sector: Chemistry

Abstract

The invention provides compounds of the formula:and pharmaceutically acceptable salts or prodrugs thereof, wherein m, p, q, r, A, E, X, Y, R1, R4, R5, R6, R7, R8, R9 and are as defined herein. The invention also provides methods for preparing, compositions comprising, and methods for using compounds of formula I.