Compounds and methods for labeling oligonucleotides
US7476735B2 · kind B2 · utility
27Cited by
68References
8Claims
0Family size
Assignee
Inventors
Key dates
| Filing date | May 22, 2006 |
| Grant date | Jan 13, 2009 |
| Priority date | — |
| Expiry date | Apr 24, 2027 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC12Q1/6818
- WIPO fieldOrganic fine chemistry
- WIPO sectorChemistry
Abstract
The invention provides a novel method of labeling oligonucleotides, with reporter moieties, including but not limited to, quenchers, fluorophores, biotin, digoxigenin, peptides and proteins. In addition, this invention provides a method of detecting hybridization of oligonucleotides. This invention also provides novel azo quenchers having the general formula shown below.The invention further provides compositions comprising labeled oligonucleotides and solid supports. The invention also provides kits comprising at least one composition of the present invention.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.