Patent · US Active

Ion fragmentation by reaction with neutral particles

US7476853B2 · kind B2 · utility

9Cited by

1References

24Claims

0Family size

Assignee

Bruker Daltonik GmbH · DE

Inventors

Roman Zubarev · Sigtuna, SE
Alexander Misharin · Columbia, US
Oleg Silivra · Uppsala, SE
Frank Kjeldsen · Uppsala, SE

Key dates

Filing date	Feb 7, 2006
Grant date	Jan 13, 2009
Priority date	—
Expiry date	Jan 20, 2027

Classification

Technology area (CPC Y)Emerging Cross-Sectional Technologies
CPC primaryY10T436/17
WIPO fieldMeasurement
WIPO sectorInstruments

Abstract

The invention relates to a method and apparatus for the fragmentation of large molecules, especially biopolymers. The invention consists in reacting analyte ions with excited or radical neutral particles, whereby, at least in the case of bombardment of analyte ions with helium atoms from an FAB generator, a new type of fragmentation occurs which strongly resembles fragmentation by electron capture (ECD). The reactions may be performed in magnetic ion traps (ion cyclotron resonance cells, ICR), in RF ion traps according to Wolfgang Paul, in RF ion guides, or in free beams of analyte ions or neutral particles.

Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.