Method of judging leukemia, pre-leukemia or aleukemic malignant blood disease and diagnostic therefor
US7479371B2 · kind B2 · utility
Assignees
Inventors
Key dates
| Filing date | Apr 9, 2003 |
| Grant date | Jan 20, 2009 |
| Priority date | — |
| Expiry date | Sep 21, 2023 |
Classification
- Technology area (CPC G)Physics
- CPC primaryG01N2333/475
- WIPO fieldMeasurement
- WIPO sectorInstruments
Abstract
The present invention relates to a method for diagnosing leukemia, pre-leukemia or aleukemic malignant blood diseases, a method of discriminating leukemia from pre-leukemia or aleukemic malignant blood diseases, a method of discriminating aplastic anemia from myelodysplastic syndrome, a method of diagnosing delayed engraftment of the hematopoietic stem cells after transplantation of the hematopoietic stem cells, and a method of diagnosing the graft versus host disease, each of said methods comprising quantifying stem cell growth factor (SCGF). The present invention also makes it possible to provide an agent for diagnosing leukemia, pre-leukemia or aleukemic malignant blood diseases and an agent for diagnosing delayed engraftment of the hematopoietic stem cells after transplantation of the hematopoietic stem cells or an agent for diagnosing graft versus host disease (GVHD), each containing as an active ingredient an antibody reacting with stem cell growth factor (SCGF).
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.