Peptides that promote lipid efflux
US7479480B2 · kind B2 · utility
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2References
6Claims
0Family size
Assignee
Inventor
Key dates
| Filing date | May 15, 2008 |
| Grant date | Jan 20, 2009 |
| Priority date | — |
| Expiry date | May 15, 2028 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC07K14/775
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
Disclosed herein are peptides with domains that promote lipid efflux from cells and optionally possess at least one anti-inflammatory domain or a domain that stimulates LCAT activity. Provided herein are methods of using the peptides to treat or inhibit diseases including dyslipidemic disorders, stroke and myocardial infarction. Also provided are methods of detecting plaque in vessels using the labeled peptides of the present invention.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.