Controlling pulses in optical microscopy
US7480045B2 · kind B2 · utility
Assignee
Inventors
Key dates
| Filing date | Oct 31, 2006 |
| Grant date | Jan 20, 2009 |
| Priority date | — |
| Expiry date | Sep 14, 2027 |
Classification
- Technology area (CPC G)Physics
- CPC primaryG01N2021/656
- WIPO fieldMeasurement
- WIPO sectorInstruments
Abstract
A method for imaging a sample is described. The sample is characterized by a limit on incident optical energy absorbed over a given time period. The method includes providing at least one input optical wave that includes pulses that each have a full-width half-maximum time duration of more than 100 picoseconds and a pulse energy sufficiently large such that a sufficient number of consecutive pulses absorbed by the sample would exceed the limit. The method also includes directing the input optical wave to focus on a first portion of the sample; detecting energy from an output optical wave generated from a nonlinear optical interaction in the first portion of the sample with the input optical wave; and generating a representation of the first portion of the sample based on the detected energy from the output optical wave.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.