Cyclic derivatives as modulators of chemokine receptor activity

US7482335B2 · kind B2 · utility

Assignee

• Bristol-Myers Squibb Company · US

Inventors

• Percy H. Carter · Princeton, US
• Robert J. Cherney · Newark, US
• Douglas G. Batt · Wilmington, US
• John V. Duncia · Newtown, US
• Daniel S. Gardner · Furlong, US
• Soo S. Ko · Hockessin, US
• Anurag S. Srivastava · Montgomery, US
• Michael G. Yang · Narberth, US

Key dates

• Filing date: Oct 10, 2006
• Grant date: Jan 27, 2009
• Expiry date: Oct 10, 2026

Classification

• Technology area (CPC C): Chemistry; Metallurgy
• CPC primary: C07D487/04
• WIPO field: Pharmaceuticals
• WIPO sector: Chemistry

Abstract

The present application describes modulators of MCP-1 of formula (I):or pharmaceutically acceptable salt forms thereof, useful for the treatment of rheumatoid arthritis, multiple sclerosis, atherosclerosis and asthma.