Indazolecarboxamide derivatives, preparation and use thereof as CDK1, CDK2 and CDK4 inhibitors

US7482342B2 · kind B2 · utility

Assignee

• Sanofi-Aventis · FR

Inventors

• Hugues D'Orchymont · Strasbourg, FR
• Luc Van Hijfte · Saint-Étienne-du-Rouvray, FR
• Andre Zimmermann · Paris, FR

Key dates

• Filing date: Apr 1, 2005
• Grant date: Jan 27, 2009
• Expiry date: Nov 10, 2026

Classification

• Technology area (CPC C): Chemistry; Metallurgy
• CPC primary: C07D471/04
• WIPO field: Pharmaceuticals
• WIPO sector: Chemistry

Abstract

Compound corresponding to general formula (I):in which, R1 represents a hydrogen or halogen atom, an NH2, NHR2, NHCOR2, NO2, CN, CH2NH2 and CH2NHR2; or alternatively R1 represents an optionally substituted phenyl or an optionally substituted heteroaromatic group;