Crystalline carbapenem intermediate
US7482445B2 · kind B2 · utility
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2References
21Claims
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Assignee
Inventors
Key dates
| Filing date | Jun 18, 2004 |
| Grant date | Jan 27, 2009 |
| Priority date | — |
| Expiry date | Aug 15, 2025 |
Classification
- Technology area (CPC A)Human Necessities
- CPC primaryA61P31/04
- WIPO fieldOrganic fine chemistry
- WIPO sectorChemistry
Abstract
This invention relates to crystals of compounds of formula (I), wherein TBS represents t-butyldimethylsilyl, and Ph represents phenyl, or its salt or solvate. Compounds of formula (I) are synthesis intermediates of 2-substituted-1β-methyl carbapenem compounds useful as antimicrobial agents. The crystals of the present invention have excellent handleability and can realize the production of carbapenem compounds having excellent antimicrobial activity in a simpler manner with improved yield and purity.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.