Patent · US Expired

Device and process for nucleophilic fluorination

US7482498B2 · kind B2 · utility

1Cited by

1References

16Claims

0Family size

Assignee

SCHERING CORPORATION · US

Inventors

Peter Maeding · Dresden, DE
Frank Fuechtner · Dresden, DE

Key dates

Filing date	May 7, 2004
Grant date	Jan 27, 2009
Priority date	—
Expiry date	Oct 29, 2025

Classification

Technology area (CPC A)Human Necessities
CPC primaryA61K51/0459
WIPO fieldPharmaceuticals
WIPO sectorChemistry

Abstract

The invention relates to a device and a process for nucleophilic fluorination of a substance, especially for synthesis of an 18F-labeled substance for examination using a positron emission tomograph. The device comprises an anion exchange device (102) for extraction of [18F]fluoride ions by means of adsorption from a target fluid, whereby the anion exchange device (102) can be charged via a supply device (101) with the target fluid; and a measurement device (104) with a measurement chamber (103) for measuring initial radioactivity of the [18F]fluoride ions, the anion exchange device (102) being arranged at least partially in the measurement chamber (103) of the measurement device (104).

Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.