Method of treating a malignancy in a subject via direct picornaviral-mediated oncolysis
US7485292B2 · kind B2 · utility
1Cited by
13References
27Claims
0Family size
Assignee
Inventor
Key dates
| Filing date | Dec 18, 2003 |
| Grant date | Feb 3, 2009 |
| Priority date | — |
| Expiry date | Jun 13, 2024 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC12N2770/32332
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
There are provided methods for treatment of abnormal cells such as cancer cells in a mammal. The methods involve treating the mammal with virus selected from echoviruses and modified forms and combination thereof, which recognize α2β1 for infectivity of the cells. There are also provided methods for screening viruses for use in a method of the invention as well as pharmaceutical compositions for use in the methods.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.