Nucleic acid encoding sodium channel subunit
US7485455B2 · kind B2 · utility
1Cited by
5References
6Claims
0Family size
Assignees
Inventors
Key dates
| Filing date | Aug 1, 2003 |
| Grant date | Feb 3, 2009 |
| Priority date | — |
| Expiry date | Jan 28, 2025 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC12Q2600/156
- WIPO fieldBiotechnology
- WIPO sectorChemistry
Abstract
The present invention discloses four groups of SCN5A variants that represent the most common SCN5A variants in humans. A specific mutation in one of the variants has been shown to display a different phenotype in relation to a human heart disease than other variants and known human sodium channel α subunits with corresponding mutations. The present invention provides new tools to study mutations and to design or identify new diagnostic and treatment strategies or agents for sodium channel related diseases or conditions.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.