Methods of inhibiting chemokine binding to chemokine receptors
US7488717B2 · kind B2 · utility
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4Claims
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Key dates
| Filing date | Aug 28, 2003 |
| Grant date | Feb 10, 2009 |
| Priority date | — |
| Expiry date | Aug 24, 2024 |
Classification
- Technology area (CPC A)Human Necessities
- CPC primaryA61K39/00
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
Novel peptides or peptidomimetic agents or small molecules for modulating the biological effect of a chemokine. According to the present invention, the therapeutic agents preferably are endowed with the capacity to bind to certain chemokines in order to modulate the biological interaction between the target ligand, chemokine, and the respective target receptor, chemokine receptor. These peptides may be described as agonist ligands or antagonists. Next, preferably certain peptides share consensus sequences are described which characterize the families or categories of these modulator peptides.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.