Indole-type derivatives as inhibitors of p38 kinase
US7488744B2 · kind B2 · utility
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32Claims
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Key dates
| Filing date | May 22, 2007 |
| Grant date | Feb 10, 2009 |
| Priority date | — |
| Expiry date | May 22, 2027 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC07D409/14
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
The invention is directed to methods to inhibit p38-α kinase using compounds comprising a phenyl or thienyl coupled through a piperidine or piperazine nucleus to an indole residue wherein the indole residue mandatorily has a substituent on the ring nitrogen which is an amino or substituted amino group.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.