Antidepressant cycloalkylamine derivatives of 2,3-dihydro-1,4-benzodioxan

US7488751B2 · kind B2 · utility

Assignee

• Wyeth, LLC · US

Inventors

• Deborah Evrard · Hamilton Square, US
• Uresh S. Shah · Cranbury, US
• Gary P. Stack · Ambler, US

Key dates

• Filing date: Mar 10, 2006
• Grant date: Feb 10, 2009
• Expiry date: May 18, 2027

Classification

• Technology area (CPC A): Human Necessities
• CPC primary: A61P43/00
• WIPO field: Pharmaceuticals
• WIPO sector: Chemistry

Abstract

Compounds of the Formula I:are useful for the treatment of depression (including but not limited to major depressive disorder, childhood depression and dysthymia), anxiety, panic disorder, post-traumatic stress disorder, premenstrual dysphoric disorder (also known as pre-menstrual syndrome), attention deficit disorder (with and without hyperactivity), obsessive compulsive disorder, social anxiety disorder, generalized anxiety disorder, obesity, eating disorders such as anorexia nervosa and bulimia nervosa, vasomotor flushing, cocaine and alcohol addiction, sexual dysfunction and related illnesses.