Patent · US Active

Method for producing 1,4-diphenyl azetidinone derivatives

US7488818B2 · kind B2 · utility

1Cited by

2References

15Claims

0Family size

Assignee

Sanofi-Aventis Deutschland GMBH · DE

Inventors

Andreas Lindenschmidt · Bad Soden, DE
David William Will · Schwalbach, DE
Gerhard Jaehne · Frankfurt, DE
Theodor Wollmann · Hofheim, DE
Wendelin Frick · Bad Camberg, DE
Bernd Junker · Bad Soden, DE
David Rigal · Frankfurt am Main, DE
Guenter Billen · Frankfurt am Main, DE
Heiner Jendralla · Frankfurt, DE

Key dates

Filing date	Nov 20, 2006
Grant date	Feb 10, 2009
Priority date	—
Expiry date	Nov 20, 2026

Classification

Technology area (CPC A)Human Necessities
CPC primaryA61P3/06
WIPO fieldPharmaceuticals
WIPO sectorChemistry

Abstract

The present invention is directed to the preparation of novel compounds useful in the treatment of hyperlipidemia, arteriosclerosis, hypercholesterolemia, and other related metabolic disorders. More specifically, the present invention is a novel process for the preparation of 1,4-diphenylazetidinone derivatives from β-substituted amino amides which are protected in the presence of silylating agents and at least one cyclization catalyst whose structural formula is represented by one of the general formula:wherein the various R-groups are defined herein.

Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.