Process for the preparation of 4-trifluoromethyl-2(1H)-pyridinone

US7488828B2 · kind B2 · utility

Assignee

• DOW AGROSCIENCES LLC · US

Inventors

• Christopher T. Hamilton · Midland, US
• Michael Gullo · Midland, US
• Michael A. Gonzalez · Portsmouth, US
• Gary Roth · Midland, US
• David B. Gorman · Midland, US
• Joachim Gebhardt · Monsheim, DE
• Norbert Gotz · Worms, DE
• Hagen Jaedicke · Ludwigshafen, DE
• Guido Mayer · Neheim, DE
• Michael Rack · Eppelheim, DE

Key dates

• Filing date: Jun 24, 2005
• Grant date: Feb 10, 2009
• Expiry date: Aug 1, 2027

Classification

• Technology area (CPC C): Chemistry; Metallurgy
• CPC primary: C07D213/64
• WIPO field: Organic fine chemistry
• WIPO sector: Chemistry

Abstract

4-Trifluoromethyl-2(1H)-pyridinone is prepared by reaction of 4-alkoxy-1,1,1-trifluorobut-3-en-2-one or 4,4-dialkoxy-1,1,1-trifluorobutan-2-one with a trialkyl phosphonoacetate followed by cyclization.