Patent · US Expired

Azolylacylguanidines as β-secretase inhibitors

US7488832B2 · kind B2 · utility

19Cited by
8References
8Claims
0Family size

Assignee

Inventors

Key dates

Filing dateFeb 13, 2006
Grant dateFeb 10, 2009
Priority date
Expiry dateFeb 13, 2026

Classification

  • Technology area (CPC C)Chemistry; Metallurgy
  • CPC primaryC07D417/12
  • WIPO fieldOrganic fine chemistry
  • WIPO sectorChemistry

Abstract

The present invention provides an azolylacylquanidine compound of formula IThe present invention also provides methods for the use thereof to inhibit β-secretase (BACE) and treat β-amyloid deposits and neurofibrillary tangles.

Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.