Synthetic peptide targeting critical sites on the SARS-associated coronavirus spike protein responsible for viral infection and method of use thereof
US7491489B2 · kind B2 · utility
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Key dates
| Filing date | Oct 28, 2005 |
| Grant date | Feb 17, 2009 |
| Priority date | — |
| Expiry date | Aug 23, 2026 |
Classification
- Technology area (CPC G)Physics
- CPC primaryG01N2333/165
- WIPO fieldMeasurement
- WIPO sectorInstruments
Abstract
The present invention provides methods for locating critical portions or sites on the spike protein (S protein) of SARS-associated coronavirus (SARS-CoV) responsible for the viral infection that causes Severe Acute Respiratory Syndrome (SARS). The present invention also provides new synthetic peptides targeting such critical portions or sites of the S protein of SARS-CoV for preventing or treating of SARS-CoV infection in a subject. The present invention further provides methods of testing antiviral activity exerted by antiviral agents using real-time quantitative PCR.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.