Method for immobilizing nucleic acid and method for manufacturing biosensor using the same method
US7491496B2 · kind B2 · utility
2Cited by
4References
13Claims
0Family size
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Key dates
| Filing date | Mar 28, 2005 |
| Grant date | Feb 17, 2009 |
| Priority date | — |
| Expiry date | May 16, 2025 |
Classification
- Technology area (CPC B)Performing Operations; Transporting
- CPC primaryB82Y30/00
- WIPO fieldBiotechnology
- WIPO sectorChemistry
Abstract
A method is provided to enable high-density absorption when immobilizing nucleic acid probes onto a solid support surface by suppressing electrostatic repulsion among the nucleic acids. A nucleic acid immobilization method to immobilize a nucleic acid onto a solid support, includes: preparing a solution containing a probe molecule which includes a nucleic acid, a spacer molecule, and at least one kind of a divalent cation; and contacting the solution with the solid support for incubation.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.