Nucleic acid formulations for gene delivery and methods of use
US7491537B2 · kind B2 · utility
4Cited by
18References
47Claims
0Family size
Assignee
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Key dates
| Filing date | Nov 20, 2006 |
| Grant date | Feb 17, 2009 |
| Priority date | — |
| Expiry date | Dec 13, 2026 |
Classification
- Technology area (CPC A)Human Necessities
- CPC primaryA61K2039/53
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
A nucleic acid formulation for use in gene delivery comprising a nucleic acid and an anionic polymer is disclosed. Examples of the anionic polymer includes anionic amino acid polymer or poly-amino acid (such as poly-L-glutamic acid, poly-D-glutamic acid, poly-L-aspartic acid, poly-D-aspartic acid), poly-acrylic acid, polynucleotides, poly galacturonic acid, and poly vinyl sulfate.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.