Patent · US Active

HCV non-structural protein mutants and uses thereof

US7491808B2 · kind B2 · utility

4Cited by

8References

14Claims

0Family size

Assignee

Novartis Vaccines and Diagnostics, Inc. · US

Inventors

David Chien · Emeryville, US
Doris Coit · Petaluma, US
Celine Hu · Tiburon, US
Sansan Lin · Albany, US
Angelica Medina-Selby · San Francisco, US

Key dates

Filing date	Aug 26, 2005
Grant date	Feb 17, 2009
Priority date	—
Expiry date	Nov 9, 2026

Classification

Technology area (CPC C)Chemistry; Metallurgy
CPC primaryC12N2770/24222
WIPO fieldMeasurement
WIPO sectorInstruments

Abstract

Modified HCV non-structural proteins are described. The proteins include modified NS3 domains such that proteolytic activity of the NS3 molecule is inhibited. The modified proteins retain conformational epitopes. HCV immunoassays including the modified NS3 molecules are also described.

Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.