Basic non-peptide bradykinin antagonists and pharmaceutical compositions therefrom
US7491825B2 · kind B2 · utility
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5References
10Claims
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Key dates
| Filing date | Jun 5, 2003 |
| Grant date | Feb 17, 2009 |
| Priority date | — |
| Expiry date | Dec 14, 2024 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC07D215/26
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
Non-peptide compounds of formula (I) having activity as specific antagonists of bradykinin (BK) B2 receptor. The compounds are chemically characterized by the presence of an alpha, alpha-disubstituted amino acid at least one amino group, free or salified, or the corresponding ammonium quaternary salt. These BK receptor antagonists are a novel class of medicaments which can be used in all the disorders in which the receptors are involved.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.