Method for assessing trait anxiety by determining cholinergic status

US7494783B2 · kind B2 · utility

Assignee

• YISSUM RESEARCH DEVELOPMENT COMPANY OF THE HEBREW UNIVERSITY OF JERUSALEM LTD. · IL

Inventors

• Hermona Soreq · Nesher, IL
• Ella Sklan · Raanana, IL
• Raz Yirmiya · Jerusalem, IL
• Keren Ailon · Mevaseret Tsiyon, IL
• Irit Shapira-Lichter · Jerusalem, IL

Key dates

• Filing date: Apr 10, 2006
• Grant date: Feb 24, 2009
• Expiry date: Oct 4, 2026

Classification

• Technology area (CPC G): Physics
• CPC primary: G01N2800/301
• WIPO field: Measurement
• WIPO sector: Instruments

Abstract

The invention provides methods/kits for assessing levels of trait or state anxiety in a subject by comparing genotypes and/or expression patterns at the ACHE, PON1 and/or BChE genes to the genotype and/or expression pattern of the genes in a reference population whose genotype and/or expression pattern of the genes is known or by correlating AChE levels activity to those of PON.