Method for producing yeast expressed HPV types 6 and 16 capsid proteins
US7494787B2 · kind B2 · utility
1Cited by
2References
8Claims
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Key dates
| Filing date | Apr 13, 2006 |
| Grant date | Feb 24, 2009 |
| Priority date | — |
| Expiry date | Jul 13, 2026 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC12N2800/108
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
Mosaic VLPs of viral capsid proteins from different virus types are described, as are methods of making the same. Specifically, a diploid yeast strain that coexpresses the L1 and L2 capsid proteins of both HPV-6 and HPV-16 as mosaic VLPs is described. The mosaic VLPs induced the production of conformational antibodies against both L1 proteins upon administration to mice.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.