Patent · US Expired

In vitro growth of tissues suitable to the formation of bone and bone forming tissue formed thereby

US7494811B2 · kind B2 · utility

32Cited by
22References
30Claims
0Family size

Assignee

Inventors

Key dates

Filing dateApr 30, 2004
Grant dateFeb 24, 2009
Priority date
Expiry dateAug 2, 2024

Classification

  • Technology area (CPC A)Human Necessities
  • CPC primaryA61L2430/02
  • WIPO fieldBiotechnology
  • WIPO sectorChemistry

Abstract

The present invention is directed to a method of growing new bone, bone-like tissue or extracellular matrix under in vitro cell culture conditions. The method utilizes a bioreactor allowing for the flow of nutrient solutions into, through, and out of the bioreactor, wherein ground demineralized bone and bone-forming cells are present in the bioreactor. The resulting bone, bone-like tissue or extracellular matrix produced by the invention are within the scope of the present invention. In addition, the present invention is directed to the bioreactor device used to grow the new bone, bone-like tissue, or extracellular matrix.

Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.