Benzimidazole derivatives and their use as GnRH antagonists

US7495110B2 · kind B2 · utility

Assignee

• Société de Conseils de Recherches et d'Applications Scientifiques (S.C.R.A.S) SAS · FR

Inventors

• Lydie Poitout · Antony, FR
• Valerie Brault · Saint-Arnoult-en-Yvelines, FR
• Eric Ferrandis · Le Puy-en-Velay, FR
• Christophe Thurieau · Paris, FR

Key dates

• Filing date: Dec 20, 2002
• Grant date: Feb 24, 2009
• Expiry date: Jul 23, 2023

Classification

• Technology area (CPC C): Chemistry; Metallurgy
• CPC primary: C07D471/10
• WIPO field: Organic fine chemistry
• WIPO sector: Chemistry

Abstract

A subject of the present application is new benzimidazole derivatives of formulain which A, Y, R1, R2, R3 and R4 represent different variable groups. These products have an antagonist activity of GnRH (Gonadotropin-Releasing Hormone). The invention also relates to pharmaceutical compositions containing said products and their use for the preparation of a medicament.