Compounds useful as serotonin inhibitors and 5-HT1A agonists and antagonists
US7495111B2 · kind B2 · utility
42Cited by
13References
42Claims
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Assignee
Inventors
Key dates
| Filing date | Jun 15, 2006 |
| Grant date | Feb 24, 2009 |
| Priority date | — |
| Expiry date | Sep 9, 2026 |
Classification
- Technology area (CPC A)Human Necessities
- CPC primaryA61P43/00
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
3-Amino chroman and 2-amino tetralin derivatives and compositions containing such compounds are disclosed. Such compounds are useful for modulating activity of a 5-HT1A receptor (agonizing or antagonizing) in a patient. These compounds are further useful for inhibiting binding to a serotonin receptor. Methods of using the 3-amino chroman and 2-amino tetralin compounds and compositions containing such compounds in the treatment of serotonin disorders, such as depression and anxiety, are also disclosed.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.