Patent · US Expired

Phospholipid derivative

US7495116B2 · kind B2 · utility

1Cited by
7References
13Claims
0Family size

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Key dates

Filing dateMar 28, 2003
Grant dateFeb 24, 2009
Priority date
Expiry dateJan 24, 2024

Classification

  • Technology area (CPC C)Chemistry; Metallurgy
  • CPC primaryC08G65/3353
  • WIPO fieldPharmaceuticals
  • WIPO sectorChemistry

Abstract

A phospholipid derivative represented by the formula (1) (Z represents a residue of a compound having 3 to 10 hydroxyl groups; AO represents an oxyalkylene group having 2 to 4 carbon atoms; R1CO and R2CO represent an acyl group having 8 to 22 carbon atoms; X represents hydrogen atom, an alkali metal atom, ammonium or an organic ammonium; “a” represents an integer of 0 to 4; “b” represents 0 or 1; Q represents hydrogen atom or methyl group; m represents an average number of moles of the oxyalkylene group added; and m, k1, k2, and k3 are numbers satisfying the following conditions: 3≦m≦200, 9≦m×(k1+k2+k3)≦1000, 1≦k1≦2, 0≦k2≦9 and 0≦k3≦9, and 3≦k1+k2+k3≦10), which is highly safe for living bodies, and is suitably used for solubilization and dispersion of physiologically active substances and the like, or in the fields of drug delivery systems such as liposomes and cosmetics.

Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.