Microfabricated chip and method of use
US7497937B2 · kind B2 · utility
Assignee
Inventors
Key dates
| Filing date | Sep 3, 2004 |
| Grant date | Mar 3, 2009 |
| Priority date | — |
| Expiry date | Jan 17, 2027 |
Classification
- Technology area (CPC G)Physics
- CPC primaryG01N27/44791
- WIPO fieldMeasurement
- WIPO sectorInstruments
Abstract
A multiplexed, absorbance-based microfabricated chip electrophoresis system, microfabricated chip, and method of use are included for the detection and identification of protein species. The microfabricated chip electrophoresis system capable of analyzing multiple samples simultaneously. The system uses a microfabricated chip having a sample chamber for first dimension separation of a sample, a first planar array of channels for second dimension separation of the sample approximately perpendicular the sample chamber, and a barrier separating the sample chamber from the first planar array of channels during the first dimension separation. In use, the sample is placed into a sample chamber, a barrier is established around the sample chamber, the sample is isoelectric focused within the sample chamber, the barrier is then removed, and the sample separated in the first array of channels by molecular weight.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.