Targeted bifunctional molecules and therapies based thereon
US7498025B1 · kind B1 · utility
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14References
29Claims
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Key dates
| Filing date | Nov 17, 2000 |
| Grant date | Mar 3, 2009 |
| Priority date | — |
| Expiry date | Apr 10, 2021 |
Classification
- Technology area (CPC A)Human Necessities
- CPC primaryA61K31/00
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
Targeted bifunctional molecules and methods for their use are provided. The subject targeted bifunctional molecules are conjugates of a drug moiety and a targeting moiety, where these two moieties are optionally joined by a linking group. The bifunctional molecules are further characterized in that they exhibit a modulated biodistribution upon administration to a host as compared to a free drug control. The subject targeted bifunctional molecules find use in a variety of therapeutic applications.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.