Photoimmunotherapies for cancer using combination therapies
US7498029B2 · kind B2 · utility
Assignee
Inventors
Key dates
| Filing date | May 1, 2002 |
| Grant date | Mar 3, 2009 |
| Priority date | — |
| Expiry date | Aug 5, 2023 |
Classification
- Technology area (CPC A)Human Necessities
- CPC primaryA61K41/0071
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
The present invention relates to photosensitizer immunoconjugate compositions and combination therapies for use in cancer related photodynamic treatments and diagnostic methods. Photosensitizer immunoconjugates comprising a photosensitizer conjugated to a tumor-specific and/or tumoricidial antibody and processes for the preparation thereof are described. The use of photosensitizer immunoconjugates (PICs) offers improved photosensitizer delivery specificity for diagnostic and therapeutic applications. Combination therapies to co-localize activated photosensitizer compounds and tumoricidal antibodies in tumor tissues are also described.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.