Method of screening cell growth inhibitor and cell growth inhibitor
US7498127B2 · kind B2 · utility
0Cited by
3References
10Claims
0Family size
Inventors
Key dates
| Filing date | Dec 19, 2003 |
| Grant date | Mar 3, 2009 |
| Priority date | — |
| Expiry date | Jun 12, 2024 |
Classification
- Technology area (CPC G)Physics
- CPC primaryG01N2500/00
- WIPO fieldMeasurement
- WIPO sectorInstruments
Abstract
The present invention provides a method for screening a cytostatic agent characterized by determining an effect of inhibiting intracellular signaling mediated by a remaining fragment of a cell membrane-anchored growth factor, and the cytostatic agent. In growth factors of the EGF family, the physiological significance of the remaining fragment is clarified, and a method for controlling its action is searched, and thus a novel pharmaceutical can be provided.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.