Keratinocytes expressing exogenous angiogenic growth factors
US7498167B2 · kind B2 · utility
9Cited by
13References
5Claims
0Family size
Inventors
Key dates
| Filing date | Apr 29, 2003 |
| Grant date | Mar 3, 2009 |
| Priority date | — |
| Expiry date | May 31, 2023 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC12N2502/99
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
The present invention relates to in vitro cultured skin tissue, and in particular to cultured skin tissue comprising exogenous genes encoding angiogenic growth factors. In some embodiments, the keratinocytes express exogenous angiopoietin-1 or a member of the VEGF family, preferably VEGF-A. In particularly preferred embodiments, the keratinocytes are incorporated into cultured skin tissue.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.