Antiarrhythmic precursor compounds, methods of synthesis and methods of use
US7498449B2 · kind B2 · utility
2Cited by
13References
6Claims
0Family size
Assignee
Inventors
Key dates
| Filing date | Jul 14, 2006 |
| Grant date | Mar 3, 2009 |
| Priority date | — |
| Expiry date | Feb 9, 2027 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC07D493/04
- WIPO fieldOrganic fine chemistry
- WIPO sectorChemistry
Abstract
The invention comprises compounds of Formula 1:wherein, R1 is independently H or halogen; R2 is, for example, H or —R10—NR11R12, and wherein R10 is C1-C6 alkyl, and R11 and R12 are independently H, C1-C4 alkyl, and hydrates, solvates, salts and tautomers thereof. The invention further comprises methods for making the compounds of the invention and methods for making compounds useful in the treatment or prevention of cardiac arrhythmia from the compounds of the invention.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.