Patent · US Active

Method for the modulation of function of transcription factors

US7501401B2 · kind B2 · utility

1Cited by

20References

25Claims

0Family size

Assignee

University of South Florida · US

Inventors

Kenneth S. Zuckerman · Tampa, US
Richard Y. Liu · Woodbury, US

Key dates

Filing date	Feb 21, 2006
Grant date	Mar 10, 2009
Priority date	—
Expiry date	Jan 7, 2027

Classification

Technology area (CPC C)Chemistry; Metallurgy
CPC primaryC12N2310/13
WIPO fieldPharmaceuticals
WIPO sectorChemistry

Abstract

There is provided a method of modulating the function of a transcription factor by administering an effective amount of an oligonucleotide containing optimal nucleotide binding site for the transcription factor. A therapeutic agent having an effective amount of an oligonucleotide for modulating function of a transcription factor and a pharmaceutically acceptable carrier is also provided. Also provided is a treatment of patients having illnesses in which the activation of transcription factors plays a role by administering to a patient an effective amount of an oligonucleotide which competitively binds the related transcription factor.

Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.