cDNAs and proteins involved in hypoxia, circadian and orphan signal transduction pathways, and methods of use
US7501489B2 · kind B2 · utility
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2Claims
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Key dates
| Filing date | Nov 29, 2005 |
| Grant date | Mar 10, 2009 |
| Priority date | — |
| Expiry date | May 31, 2026 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC07K14/4702
- WIPO fieldBiotechnology
- WIPO sectorChemistry
Abstract
The present invention provides isolated nucleic acids and proteins that are new and distinct members of the bHLH-PAS superfamily of transcription regulators. These “MOPs” (members of PAS) are useful in a variety of research, diagnostic and therapeutic applications. Several of the MOPs of the present invention are α-class hypoxia-inducible factors. Several other of the MOPs of the invention are involved in circadian signal transduction.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.