Enantiomeric resolution of 2-substituted 4-substituted 1,3-oxathiolanes nucleosides
US7501514B1 · kind B1 · utility
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23Claims
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Key dates
| Filing date | Oct 15, 2004 |
| Grant date | Mar 10, 2009 |
| Priority date | — |
| Expiry date | Mar 8, 2026 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC07D411/04
- WIPO fieldOrganic fine chemistry
- WIPO sectorChemistry
Abstract
Single enantionmers of compounds of formula (B), in either the cis or trans configuration,wherein R1 and R2 are as defined herein, can be separated from enantiomeric mixtures thereof by reacting the compound with an acid to produce a conglomerate salt that has the following characteristics:
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.