Methods and apparatus for amplification of DNA using sonic energy
US7504219B2 · kind B2 · utility
4Cited by
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18Claims
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Key dates
| Filing date | May 12, 2006 |
| Grant date | Mar 17, 2009 |
| Priority date | — |
| Expiry date | May 12, 2026 |
Classification
- Technology area (CPC B)Performing Operations; Transporting
- CPC primaryB01L2400/0439
- WIPO fieldMeasurement
- WIPO sectorInstruments
Abstract
Apparatus and methods for amplification of DNA are provided that use sonic energy in place of conventional thermocyclers. In one embodiment, sonic energy is applied to a PCR cocktail to effect dissociation of double stranded DNA into single strands of DNA. A quiescence stage, where no sonic energy is applied, results in amplification of DNA. Repetition of the cycles of application of sonic energy and cessation of application of sonic energy results in DNA amplification.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.