Patent · US Active

Macrocyclic peptides active against the hepatitis C virus

US7504378B2 · kind B2 · utility

34Cited by

10References

25Claims

0Family size

Assignee

Boehringer Ingelheim International GmbH · DE

Inventors

Montse Llinas-Brunet · Dollard-Des-Ormeaux, CA
Murray D. Bailey · Laval, CA

Key dates

Filing date	Dec 10, 2005
Grant date	Mar 17, 2009
Priority date	—
Expiry date	Nov 7, 2026

Classification

Technology area (CPC A)Human Necessities
CPC primaryA61K38/00
WIPO fieldPharmaceuticals
WIPO sectorChemistry

Abstract

Compounds of formula (I):wherein R1 is (C1-8)alkyl, (C3-7)cycloalkyl, {(C1-6)alkyl-(C3-7)cycloalkyl} or Het, which are all optionally substituted from 1 to 3 times with halo, cyano, nitro, O—(C1-6)alkyl, amido, amino or phenyl, or R1 is C6 or C10 aryl which is optionally substituted from 1 to 3 times with halo, cyano, nitro, (C1-6)alkyl, O—(C1-6)alkyl, amido, amino or phenyl; or a pharmaceutically acceptable salt thereof, useful as an inhibitor of the HCV NS3 protease.

Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.