RNA polymerase III promoter, process for producing the same and method of using the same
US7504492B2 · kind B2 · utility
Inventors
Key dates
| Filing date | Feb 16, 2004 |
| Grant date | Mar 17, 2009 |
| Priority date | — |
| Expiry date | Oct 5, 2024 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC12N2830/85
- WIPO fieldBiotechnology
- WIPO sectorChemistry
Abstract
The present invention provides an RNA polymerase III promoter characterized in that a part of its sequence is substituted with a sequence capable of undergoing specific DNA recombination by Cre recombinase in such a manner functions of PSE and a TATA box are not impaired. This RNA polymerase III promoter can be used in a RNAi induction method with the condition that RNAi molecules to be used in analyzing gene function can be induced at an arbitrary point of time or only in a specific tissue (organ).
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.