Patent · US Active

PGD2 receptor antagonists for the treatment of inflammatory diseases

US7504508B2 · kind B2 · utility

7Cited by

16References

2Claims

0Family size

Assignee

Millennium Pharmaceuticals, Inc. · US

Inventors

Shomir Ghosh · Brookline, US
Amy Elder · Arlington, US
Kenneth G. Carson · Princeton, US
Kevin Sprott · Needham, US
Sean J. Harrison · Belmont, US
Frederick A. Hicks · Somerville, US
Christelle C. Renou · Stoneham, US
Dominic Reynolds · Stoneham, US

Key dates

Filing date	Apr 7, 2005
Grant date	Mar 17, 2009
Priority date	—
Expiry date	Jun 27, 2026

Classification

Technology area (CPC C)Chemistry; Metallurgy
CPC primaryC07D417/06
WIPO fieldOrganic fine chemistry
WIPO sectorChemistry

Abstract

Disclosed herein are compounds represented by Structural Formula (I) and (I-A):Also disclosed is the use of such compounds for inhibiting the G-protein coupled receptor referred to as chemoattractant receptor-homologous molecule expressed on Th2, or simply “CRTH2” for the treatment of inflammatory disorders. The variables in Structural Formula (I) and (I-A) are defined herein.

Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.