Compounds and methods for development of Ret modulators
US7504509B2 · kind B2 · utility
125Cited by
57References
39Claims
0Family size
Assignee
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Key dates
| Filing date | Dec 17, 2004 |
| Grant date | Mar 17, 2009 |
| Priority date | — |
| Expiry date | Mar 16, 2026 |
Classification
- Technology area (CPC A)Human Necessities
- CPC primaryA61P35/00
- WIPO fieldOrganic fine chemistry
- WIPO sectorChemistry
Abstract
Compounds active on Ret are described, as well as methods of using such compounds. Also described are crystal structures of Ret surrogates that were determined using X-ray crystallography. The use of such Ret surrogate crystals and structural information can, for example, be used for identifying molecular scaffolds and for developing ligands that bind to and modulate Ret and for identifying improved ligands based on known ligands.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.