Method for regulating immune function using the FOXP3 protein
US7507542B2 · kind B2 · utility
Assignee
Inventors
Key dates
| Filing date | May 8, 2002 |
| Grant date | Mar 24, 2009 |
| Priority date | — |
| Expiry date | Oct 1, 2022 |
Classification
- Technology area (CPC G)Physics
- CPC primaryG01N2500/20
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
Isolated nucleic acid molecules are provided which encode Fkhsf, as well as mutant forms thereof. Also provided are expression vectors suitable for expressing such nucleic acid molecules, and host cells containing such expression vectors. Also provided are pharmaceutical compounds and methods of identifying such compounds that can modulate the immune system. In addition are provided methods for identifying proteins regulated by Scurfin (Fkhsf) and proteins that induce or inhibit Scurfin or Foxp3 expression.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.