Cytokine receptor chain

US7507706B1 · kind B1 · utility

Assignee

• Genetics Institute, LLC · US

Inventors

• Mary Collins · Natick, US
• Debra Donaldson · Cambridge, US
• Lori Fitz · Arlington, US
• Tamlyn Neben · Acton, US
• Matthew Whitters · Hudson, US
• Clive Wood · Boston, US
• Marsha Wills-Karp · Baltimore, US

Key dates

• Filing date: Dec 13, 1999
• Grant date: Mar 24, 2009
• Expiry date: Dec 13, 2019

Classification

• Technology area (CPC C): Chemistry; Metallurgy
• CPC primary: C07K2319/02
• WIPO field: Pharmaceuticals
• WIPO sector: Chemistry

Abstract

Polynucleotides encoding the IL-13 receptor and fragments thereof are disclosed. IL-13 receptor proteins, methods for their production, inhibitors of binding of IL-13 and its receptor and methods for their identification are also disclosed. Methods of medical treatment using such molecules and antagonists of the IL-13/IL-13R interaction are also provided.