Synergistic effects of OP/BMP morphogens and GDNF/NGF neurotrophic factors
US7507709B2 · kind B2 · utility
0Cited by
3References
10Claims
0Family size
Assignee
Inventors
Key dates
| Filing date | Mar 18, 2005 |
| Grant date | Mar 24, 2009 |
| Priority date | — |
| Expiry date | Nov 22, 2025 |
Classification
- Technology area (CPC A)Human Necessities
- CPC primaryA61K38/1875
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
OP/BMP morphogen may be combined with GDNF/NGF neurotrophic factors to promote the survival or growth, or inhibit the death or degeneration, of mammalian cells, particularly neural cells, which express OP/BMP-activated serine/threonine kinase receptors and GDNF/NGF-activated tyrosine kinase receptors. Also disclosed are methods for the treatment of such cells, including treatments for mammals afflicted with, or at imminent risk of, damage or injury to, such cells, as well as new pharmaceutical preparations for such treatments.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.