Therapeutic ion channel blocking agents and methods of use thereof
US7507839B2 · kind B2 · utility
0Cited by
7References
4Claims
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Key dates
| Filing date | Mar 20, 2003 |
| Grant date | Mar 24, 2009 |
| Priority date | — |
| Expiry date | Jul 31, 2024 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC07D409/14
- WIPO fieldOrganic fine chemistry
- WIPO sectorChemistry
Abstract
Various divalent ligands based on khellinone derivatives are described. These derivatives can be useful in the modulation of potassium channel activity in cells, including among others Kv1.3 channels found in T-cells. The compounds may also be useful in the treatment or prevention of autoimmune and inflammatory diseases, including multiple sclerosis.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.