Histone deacetylase inhibitors
US7507858B2 · kind B2 · utility
9Cited by
5References
11Claims
0Family size
Assignee
Inventors
Key dates
| Filing date | Jul 15, 2005 |
| Grant date | Mar 24, 2009 |
| Priority date | — |
| Expiry date | Nov 2, 2025 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC07D277/82
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
This invention relates to iminodiacetic acid and diamine hydroxamic acid derivatives, that are inhibitors of histone deacetylase (HDAC), and are useful in the prevention and/or treatment of cellular proliferative diseases, for example cancer, autoimmune, allergic and inflammatory diseases, diseases of the central nervous system (CNS) such as neurodegenerative diseases, and in the prevention and/or treatment of restenosis.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.